AdvancedCPR Solutions® LLC (ACS), develops and markets solutions to potentially improve survival outcomes from sudden cardiac arrest — the leading cause of death in the US and Europe of adults over 40 years of age, and the third largest cause of death overall (estimated at >470,000/yr. in the US).1
Sudden Cardiac Arrest (SCA)
Sudden cardiac arrest, the abrupt loss of heart function that occurs when the heart’s electrical system malfunctions, is a leading cause of death globally, claiming a life every 90 seconds and taking more lives annually than breast cancer, lung cancer and HIV/AIDs combined.2
The ElevatedCPR™ Method
The ElevatedCPR method is a technologically-advanced technique for performing controlled sequential device-assisted head up CPR that incorporates raising the head, heart, and thorax in a multi-level elevation, in a timed sequence, in conjunction with best practice resuscitation protocols.
Founded in Minneapolis, MN as Minnesota Resuscitation Solutions in 2015, AdvancedCPR Solutions is the pioneer of the ElevatedCPR method, a broad, patent-protected evidence-based resuscitation technique centered on patient positioning that could potentially improve survival of sudden cardiac arrest. Our early stage medical device firm is focused on the development and commercialization of delivery mechanisms, methods, and devices that support the practice of the ElevatedCPR method to potentially improve survival of cardiac arrest.
The Science Behind the ElevatedCPR Method
Preclinical studies have demonstrated a number of benefits associated with the ElevatedCPR method relative to intracranial pressure (ICP)5,6,7 cerebral perfusion pressure (CerPP)5,6,7,8,9,10,11 and coronary perfusion pressure (CorPP).6,7,8,9,10,11
The ElevatedCPR method is used in conjunction with best practice standards including active compression-decompression CPR (ACD-CPR) or mechanical CPR devices and an impedance threshold device (ITD) to help regulate intrathoracic pressure while CPR is being performed.
Preclinical studies exploring the ElevatedCPR method as part of this bundle of care have shown a strong potential to improve resuscitation and survival from sudden cardiac arrest.5,6,9,12
The EleGARDTM Patient Positioning System is the only device that precisely and consistently elevates a patient’s head and thorax from supine to multi-level positioning and could support the practice of the ElevatedCPR method.13 It is intended to elevate a patient’s head and thorax during airway management and during manual CPR, manual CPR adjuncts, CPR with the LUCAS® Chest Compression System; and patient transport.
Clinical results from early adopters in high performing EMS Services indicate that the ElevatedCPR Method, including use of the EleGARD Patient Positioning System, has provided significant benefits to patients, including:
— 10% increase in Return of Spontaneous Circulation (ROSC) compared to simple head elevation in PEA and asystole patients13
— 10% increase in neurologically-intact survival14
1. American Heart Association Statistics, Update 2018
3. “Annual Incidence of Adult and Pediatric In-Hospital Cardiac Arrest in the United States”.Circulation: Cardiovascular Quality and Outcomes, July 2019.
4. Cardiac Arrest Registry to Enhance Survival (CARES) 2018
5. Debaty, et al., Resuscitation, 2015
6. Ryu, et al., Resuscitation, 2016
7. Moore, et al., Resuscitation, 2018
8. Kim, et al., Resuscitation, 2017
9. Moore, et al., Circulation, 2018
11. Frascone, Gathering of Eagles, 2019
12. Moore, American Heart Association, Resuscitation, 2019
13. Scheppke, Prehospital Emergency Care, 2020
14. Lick, Presentation at EMS Today, 2020
AdvancedCPR Solutions Receives Clearance for Expanded Indications for Use of EleGARD™ Patient Positioning System
April 27, 2020